| Addiction Services Central Ontario, South Simcoe Community RAAM - Alliston, Rapid Access Addiction Medicine Clinic, South Simcoe | New Tecumseth |
| Barrie Peoples Clinic & Pharmacy, South Barrie, Addiction Treatment | Barrie |
| Brightshores Health System, Brockton, Mental Health and Addiction Services Department - Rapid Access Addiction Medicine Clinic | Walkerton |
| Brightshores Health System, Durham - South Bruce Grey Health Centre, Mental Health and Addiction Services Department - Rapid Access Addiction Medicine Clinic | |
| Brightshores Health System, Hanover and District Hospital, Mental Health and Addiction Services Department - Rapid Access Addiction Medicine Clinic | Hanover |
| Brightshores Health System, Kincardine, Mental Health and Addiction Services Department - Rapid Access Addiction Medicine Clinic | Kincardine |
| Brightshores Health System, Lion's Head Hospital, Mental Health and Addiction Services Department - Rapid Access Addiction Medicine Clinic | Northern Bruce Peninsula |
| Brightshores Health System, Meaford - Sykes St N, Mental Health and Addiction Services Department - Rapid Access Addiction Medicine Clinic | Meaford |
| Brightshores Health System, Neyaashiinigmiing, Mental Health and Addiction Services Department - Rapid Access Addiction Medicine Clinic | Neyaashiinigmiing |
| Brightshores Health System, Owen Sound - 6th St 'A' E, Mental Health and Addiction Services Department - Rapid Access Addiction Medicine Clinic | Owen Sound |
| Brightshores Health System, Port Elgin, Mental Health and Addiction Services Department - Rapid Access Addiction Medicine Clinic | Saugeen Shores |
| Brightshores Health System, Wiarton Hospital, Mental Health and Addiction Services Department - Rapid Access Addiction Medicine Clinic | South Bruce Peninsula |
| Canadian Mental Health Association, Muskoka-Parry Sound, Parry Sound Office, Addiction Services | Parry Sound |
| Canadian Mental Health Association. Simcoe County Branch, Barrie - 99 Ferris Lane, Addiction Services | Barrie |
| Canadian Mental Health Association. Simcoe County Branch, Collingwood - 186 Erie St - Suite 101, Addiction Services | Collingwood |
| Canadian Mental Health Association. Simcoe County Branch, Midland, Addiction Services | Midland |
| Grey Bruce Public Health, Needle Syringe Exchange and Naloxone Program | Owen Sound |
| Right to Heal, Peterborough | Peterborough |
| Royal Victoria Regional Health Centre, Barrie - 5 Quarry Ridge Rd, North Simcoe Muskoka Rapid Access Addiction Medicine Services | Barrie |
| Royal Victoria Regional Health Centre, Midland - Bayshore Dr, North Simcoe Muskoka Rapid Access Addiction Medicine Services | Midland |
| Royal Victoria Regional Health Centre, Orillia Common Roof - Front St S, North Simcoe Muskoka Rapid Access Addiction Medicine Services | Orillia |
| Royal Victoria Regional Health Centre, Wasaga Beach, North Simcoe Muskoka Rapid Access Addiction Medicine Services | Wasaga Beach |
| South East Grey Community Health Centre, Dundalk - Artemesia St S (Erskine Centre), Rapid Access Addiction Medicine Clinic | Southgate |