| 1door | Barrie |
| Addiction Services Central Ontario, South Simcoe Community RAAM - Alliston, Rapid Access Addiction Medicine Clinic, South Simcoe | New Tecumseth |
| Back on Track - Ontario's Remedial Measures Program for Impaired Drivers, Toronto - Mailing Address | Toronto |
| Barrie Area Native Advisory Circle, Barrie - 125 Bell Farm Rd, Suite 200, Mamaway Wiidokdaadwin Clinic | Barrie |
| Barrie Area Native Advisory Circle, Orillia, Mamaway Wiidokdaadwin Clinic | Orillia |
| Barrie Native Friendship Centre, Barrie - 175 Bayfield St, Urban Indigenous Healthy Living | Barrie |
| Bradford Medical Centre | Bradford West Gwillimbury |
| Busby Centre, Barrie - 88 Mulcaster St, Drop In Services | Barrie |
| Busby Centre, Barrie - 88 Mulcaster St, Emergency Respite Shelter | Barrie |
| Busby Centre, Barrie - 88 Mulcaster St, Outreach Program | Barrie |
| Canadian Cancer Society, Mailing Address, Cancer Information and Transportation Service | |
| CONTACT Community Services, Exchange WORKS, Alliston - 39 Victoria St E | New Tecumseth |
| Hopewood Clinic, Angus, Angus Rapid Access Addiction Medicine (RAAM) Clinic | Essa |
| Hospital for Sick Children, Adolescent Medicine | Toronto |
| John Howard Society of Simcoe & Muskoka, Barrie - 78 Mulcaster | Barrie |
| John Howard Society of Simcoe & Muskoka, Orillia - 17 Colborne St E | Orillia |
| LifeLabs, Innisfil, Medical Laboratory Services | Innisfil |
| MADD Canada, Mailing Address, Barrie Simcoe Chapter | Barrie |
| Ontario Addiction Treatment Centres, Alliston Office | New Tecumseth |
| Reflection Centre, Barrie | Barrie |
| Road to Recovery Addiction Clinic, Bradford, Addiction Clinic | Bradford West Gwillimbury |
| Royal Victoria Regional Health Centre, Barrie - 70 Wellington St W - Upper Level, Withdrawal Management Services | Barrie |
| S.H.I.F.T, Daytime Drop-In Centre Program | New Tecumseth |
| S.H.I.F.T, Mobile Outreach Program | New Tecumseth |
| Salvation Army (The), Hope Acres, Hope Acres Addiction Treatment Centre | Adjala-Tosorontio |
| Simcoe Muskoka District Health Unit, Cookstown Branch - 25 King St S, Environmental Health Department | Innisfil |
| Simcoe Muskoka District Health Unit, Various locations, Substance Use Prevention and Harm Reduction Programs | |
| Simcoe Muskoka Opioid Strategy, Online / Web Service | Barrie |
| Towards Recovery Clinic, Barrie, Towards Recovery Clinic, Barrie | Barrie |
| Waypoint Centre for Mental Health Care, Penetanguishene - 500 Church St - Toanche Bldg, Georgianwood Program for Concurrent Disorders | Penetanguishene |
| Words Of Hope Counselling Services | Barrie |
| YMCA of Simcoe/Muskoka, Barrie - Bayfield St, Youth in Transition Worker Program | Barrie |