| S.H.I.F.T, Daytime Drop-In Centre | New Tecumseth |
| S.H.I.F.T, Emergency Overnight Shelter Program | New Tecumseth |
| S.H.I.F.T, Mobile Outreach Program | New Tecumseth |
| SafeCirc Newborn Circumcision Clinic | Barrie |
| Salvation Army (The), Collingwood, Collingwood Food Bank | Collingwood |
| Salvation Army (The), Hope Acres, Hope Acres Addiction Treatment Centre | Glencairn |
| Salvation Army Barrie, Barrie - Bayfield St, Barrie Bayside Mission Centre - Family Emergency Shelter Program | Barrie |
| Salvation Army Barrie, Barrie - Bayfield St, Barrie Bayside Mission Centre - Men's Emergency Shelter | Barrie |
| Salvation Army Barrie, Barrie - Bayfield St, Community and Family Services | Barrie |
| Salvation Army Barrie, Barrie - Essa Rd, Thrift Store | Barrie |
| Salvation Army Barrie, Barrie - Lillian Cres, Community Church | Barrie |
| Salvation Army Barrie, Barrie - Mulcaster St, Simcoe County and Muskoka District Bail Verification and Supervision Program | Barrie |
| Salvation Army Barrie, Gravenhurst, Simcoe County and Muskoka District Bail Verification and Supervision Program | Gravenhurst |
| Salvation Army Orillia Citadel (The), Orillia - Coldwater Rd W, Christmas Hamper Program | Orillia |
| Samaritan House | Barrie |
| Sandbox Centre, Barrie | Barrie |
| Science North, Mailing Address, Summer Day Camps | Simcoe |
| SCORE Hockey League | Barrie |
| Scottish Connection | Barrie |
| Scottish Rite, Valley of Barrie, Valley of Barrie Scottish Rite | Barrie |
| Scouts Canada | Simcoe |
| Seasons Centre for Grieving Children | Barrie |
| Seconds Wholesale | Innisfil |
| SEIU Healthcare | Barrie |
| Senior Wish Association (Simcoe County), Mailing Address, Senior Wish Association | Barrie |
| Seniors Housing Alliance Simcoe County - Creative Options for Aging Well, Mailing Address | Barrie |
| Service Canada | Ontario |
| Service Canada, Barrie, Canada Disability Benefit | Barrie |
| Service Canada, Barrie, Canada Pension Plan Disability Benefits | Barrie |
| Service Canada, Barrie, Canada Pension Plan Survivor's Benefits - Children's Benefit | Barrie |
| Service Canada, Barrie, Canada Pension Plan Survivor's Benefits - Death Benefits | Barrie |
| Service Canada, Barrie, Canada Pension Plan Survivor's Benefits - Survivor's Pension | Barrie |
| Service Canada, Barrie, Canada Pension Plan | Barrie |
| Service Canada, Barrie, Canadian Dental Care Plan | Barrie |
| Service Canada, Barrie, Employment Insurance, Barrie | Barrie |
| Service Canada, Barrie, Old Age Security - Allowance for the Survivor | Barrie |
| Service Canada, Barrie, Old Age Security - Allowance | Barrie |
| Service Canada, Barrie, Old Age Security - Guaranteed Income Supplement | Barrie |
| Service Canada, Barrie, Old Age Security - Pension | Barrie |
| Service Canada, Barrie, Opportunities Fund for Persons with Disabilities | Barrie |
| Service Canada, Barrie, Service Canada Centre, Barrie | Barrie |
| Service Canada, Collingwood, Service Canada Centre | Collingwood |
| Service Canada Scheduled Outreach Site, Alliston, Federal Government Services | New Tecumseth |
| ServiceOntario, Alliston, Alliston Service Counter | New Tecumseth |
| ServiceOntario, Barrie - Bayfield St, Barrie (Bayfield St) Service Counter | Barrie |
| ServiceOntario, Barrie - Burton Ave, Barrie (Burton Ave) Service Counter | Barrie |
| ServiceOntario, Barrie - Simcoe St, Barrie (Simcoe St) Service Counter | Barrie |
| ServiceOntario, Barrie - Worsley St, Barrie Land Registry Office 51 | Barrie |
| ServiceOntario, Bradford, Bradford Service Counter | Bradford West Gwillimbury |
| ServiceOntario, Office of the Registrar General | Toronto |
| Sevenoaks Academy, Barrie | Barrie |
| Sexaholics Anonymous Ontario, Barrie - No Physical Address, Sexaholics Anonymous Barrie | Barrie |
| Sheba Shrine Club of Barrie, Sheba Shrine Club and Traditions Banquet Hall | Barrie |
| Shoebox Project for Women (The), Mailing Address, Simcoe and Grey County Chapter | Barrie |
| Sienna Senior Living, Creedan Valley Community | Creemore |
| Simcoe / Muskoka Supervised Access Centre | Midland |
| Simcoe Childcare Services, Innisfil - 25th Sdrd, Before and After School Program | Innisfil |
| Simcoe Childcare Services, Innisfil - St Paul Rd | Innisfil |
| Simcoe Community Access Network Development Corporation | Barrie |
| Simcoe Contemporary Dancers, No Physical Address | Barrie |
| Simcoe County Airport Service | Barrie |
| Simcoe County Archives | Springwater |
| Simcoe County Arts and Crafts Association, Mailing Address | Springwater |
| Simcoe County Band | Barrie |
| Simcoe County Chess Club | Barrie |
| Simcoe County Child Care Committee | Springwater |
| Simcoe County District School Board, Adult Learning and Continuing Education Department, Midhurst - Education Centre | Springwater |
| Simcoe County District School Board, Alliston - 46 Wellington St W, Unit 3, Simcoe Shores Secondary Schools | New Tecumseth |
| Simcoe County District School Board, Alliston Learning Centre Campus, Learning Centre, Alliston Learning Centre Campus | New Tecumseth |
| Simcoe County District School Board, Alliston Learning Centre Campus, Literacy and Basic Skills | New Tecumseth |
| Simcoe County District School Board, Angus, Simcoe Shores Secondary Schools | Essa |
| Simcoe County District School Board, Barrie Learning Centre, Adult English as a Second Language | Barrie |
| Simcoe County District School Board, Barrie Learning Centre | Barrie |
| Simcoe County District School Board, Barrie Learning Centre, Newcomer Welcome Centre | Barrie |
| Simcoe County District School Board, Bradford - 157 Holland St E, Unit 6A, Simcoe Shores Secondary Schools | Bradford West Gwillimbury |
| Simcoe County District School Board, Bradford Learning Centre Campus, Adult High School Diploma Program, Bradford Campus | Bradford West Gwillimbury |
| Simcoe County District School Board, Bradford Learning Centre Campus, Learning Centre, Bradford Campus | Bradford West Gwillimbury |
| Simcoe County District School Board, Bradford Learning Centre Campus, Literacy and Basic Skills | Bradford West Gwillimbury |
| Simcoe County District School Board, Collingwood Learning Centre Campus, Simcoe Shores Secondary Schools | Collingwood |
| Simcoe County District School Board, Education Centre - Midhurst, Trustees - Essa, CFB Borden, Adjala-Tosoronto | Midhurst |
| Simcoe County District School Board, Education Centre - Midhurst, Trustees - Innisfil | Midhurst |
| Simcoe County District School Board, Education Centre - Midhurst, Trustees - New Tecumseth, Bradford West Gwillimbury | Midhurst |
| Simcoe County District School Board, Innisfil, Simcoe Shores Secondary Schools | Innisfil |
| Simcoe County District School Board, Midhurst - Education Centre, Before and After School Programs | Springwater |
| Simcoe County District School Board, Midhurst - Education Centre, Classroom Meeting Facilities | Springwater |
| Simcoe County District School Board, Midhurst - Education Centre | Springwater |
| Simcoe County District School Board, Midhurst - Education Centre, Trustee - First Nation Communities | Springwater |
| Simcoe County District School Board, Ontario Youth Apprenticeship Program, Midhurst - Education Centre | Springwater |
| Simcoe County Embroidery Guild | Springwater |
| Simcoe County Families in TRANSition, Online / Virtual Service | Barrie |
| Simcoe County Federation of Agriculture, Simcoe County Administration Building | Springwater |
| Simcoe County Greenbelt Coalition, Mailing Address | Simcoe |
| Simcoe County Historical Association | Barrie |
| Simcoe County Home Builders' Association | Barrie |
| Simcoe County Master Gardeners | Springwater |
| Simcoe County Museum | Minesing |
| Simcoe County Quilters Guild, Simcoe County Quilters' Guild | Barrie |
| Simcoe County Rovers FC | Barrie |
| Simcoe County Student Transportation Consortium | Barrie |
| Simcoe County Suicide Awareness Council, No Physical Address | Barrie |
| Simcoe County Young Professionals Association | Barrie |
| Simcoe County, Corporation of, Alliston Ontario Works Office, Ontario Works | New Tecumseth |
| Simcoe County, Corporation of, Barrie Public Library, Ontario Works | Barrie |
| Simcoe County, Corporation of, Bradford Ontario Works Office, Ontario Works | Bradford West Gwillimbury |
| Simcoe County, Corporation of, Collingwood Ontario Works Office, Ontario Works | Collingwood |
| Simcoe County, Corporation of, Elmvale, Long Term Care and Seniors Services - Adult Day Program | Springwater |
| Simcoe County, Corporation of, Midhurst Administration Centre, Children and Community Services - LEAP Program | Springwater |
| Simcoe County, Corporation of, Midhurst Administration Centre, Children Services | Springwater |
| Simcoe County, Corporation of, Midhurst Administration Centre, Homelessness Services | Springwater |
| Simcoe County, Corporation of, Midhurst Administration Centre, Housing Programs - Home Ownership Program | Springwater |
| Simcoe County, Corporation of, Midhurst Administration Centre, One-time top-up to the Canada Housing Benefit | Springwater |
| Simcoe County, Corporation of, Midhurst Administration Centre, Social Housing - Housing Retention Program | Springwater |
| Simcoe County, Corporation of, Midhurst Administration Centre, Social Housing Department | Springwater |
| Simcoe County, Corporation of, Midland Ontario Works Office, Ontario Works | Midland |
| Simcoe County, Corporation of, Orillia Ontario Works Office, Ontario Works | Orillia |
| Simcoe County, Corporation of, Penetanguishene, Long Term Care and Seniors Services - Adult Day Program | Penetanguishene |
| Simcoe Huronia Home Services | Barrie |
| Simcoe Ladies Fast Pitch League, Simcoe County - No Physical Address | Simcoe |
| Simcoe Muskoka Catholic District School Board, Barrie - Alliance Blvd, Catholic Education Centre | Barrie |
| Simcoe Muskoka Catholic District School Board, Barrie - Alliance Blvd, Community Use of Schools | Barrie |
| Simcoe Muskoka Catholic District School Board, Barrie - Alliance Blvd, Ontario Youth Apprenticeship Program | Barrie |
| Simcoe Muskoka District Health Unit, Alliston, Breastfeeding Support Group | New Tecumseth |
| Simcoe Muskoka District Health Unit, Angus, Prenatal Classes | Angus |
| Simcoe Muskoka District Health Unit, Barrie - 80 Bradford St, Dental Screening and Dental Clinics | Barrie |
| Simcoe Muskoka District Health Unit, Barrie - 80 Bradford St, Sexual Health Counselling, Education and Clinic Services | Barrie |
| Simcoe Muskoka District Health Unit, Barrie Head Office - 15 Sperling Dr | Barrie |
| Simcoe Muskoka District Health Unit, Bradford West Gwillimbury Community Hub, Prenatal Classes | Bradford West Gwillimbury |
| Simcoe Muskoka District Health Unit, Bradford, Breastfeeding Support Group | Bradford West Gwillimbury |
| Simcoe Muskoka District Health Unit, Cookstown Branch - 25 King St S, Environmental Health Department | Innisfil |
| Simcoe Muskoka District Health Unit, Cookstown Branch - 25 King St S, Immunization Program | Innisfil |
| Simcoe Muskoka District Health Unit, Cookstown Branch - 25 King St S | Innisfil |
| Simcoe Muskoka District Health Unit, Gravenhurst Branch - 5 Pineridge Gate, Dental Screening and Dental Clinics | Gravenhurst |
| Simcoe Muskoka District Health Unit, Various locations, Substance Use Prevention and Harm Reduction Programs | |
| Simcoe Muskoka Family Connexions, Barrie Office, Child Welfare, Adoption and Foster Care Services | Barrie |
| Simcoe Muskoka Family Connexions, Barrie Office, Communications, Community Relations and Fundraising | Barrie |
| Simcoe Muskoka Opioid Strategy, Online / Web Service | Barrie |
| Simcoe Muskoka Skillforce, Orillia, Literacy and Basic Skills Support Organization | Orillia |
| Simcoe Muskoka Skillforce, Orillia, Local Board | Orillia |
| Simcoe Peer Support for Mental Health and Addictions | Collingwood |
| Simcoe Peer Support for Mental Health and Addictions, Collingwood | Collingwood |
| Simcoe Village Apartments, Supportive Housing | New Tecumseth |
| Simplifeye Mobile Optical, Simcoe County, Community Vision Clinics | Penetanguishene |
| Simplifeye Mobile Optical, Simcoe County, Mobile In-Home Optician Services | Penetanguishene |
| Sir Frederick Banting Legacy Foundation, Banting Homestead Heritage Park, Diabetes Management and Education Centre | New Tecumseth |
| Ski Snow Valley | Springwater |
| Smiles4miles, Mobile Service, Mobile/Onsite Dental Hygiene Clinic | Aurora |
| Social Benefits Tribunal | Toronto |
| Society for Creative Anachronism, Barrie - Mailing Address | Barrie |
| Society of Saint Vincent de Paul | Collingwood |
| Society of Saint Vincent de Paul, Barrie - Baldwin Lane, St John Vianney Conference | Barrie |
| Society of Saint Vincent de Paul, Collingwood, St Mary's Conference | Collingwood |
| Society of Saint Vincent de Paul, No Physical Address, St Mary's Conference | Barrie |
| Society of Saint Vincent de Paul - Guardian Angels Conference, Orillia, Food Bank | Orillia |
| Society of St Vincent de Paul, Alliston, St Paul's Alliston Conference | New Tecumseth |
| Society of St Vincent de Paul, Midland, St Margaret's Conference, Food Pantry | Midland |
| Society of St Vincent de Paul, Penetanguishene, St Ann's Conference | Penetanguishene |
| Society of St. Vincent de Paul - St Patrick's / St Noel Chabanel Conference, Wasaga Beach, Christmas Assistance | Wasaga Beach |
| South Asian Association of Simcoe County | Barrie |
| South Simcoe Dufferin Track and Field Club | Barrie |
| South Simcoe Medical Walk-in Clinic | Bradford West Gwillimbury |
| South Simcoe Police, Bradford - South Division | Bradford West Gwillimbury |
| South Simcoe Police, Innisfil - North Division | Innisfil |
| South Simcoe Rebel Rollers Roller Derby League | Orillia |
| Special Olympics Ontario - Central Ontario, South Simcoe - Mailing Address, Special Olympics Ontario - South Simcoe Chapter | New Tecumseth |
| Specialty Transportation By Park Place Plus, Mailing Address | New Tecumseth |
| Spinal Cord Injury Ontario [Central East], Barrie, Barrie Regional Office | Barrie |
| Springwater United Soccer Academy | Minesing |
| St Andrew's Society of Simcoe County, Mailing Address | Barrie |
| St John Ambulance, Barrie Simcoe Muskoka, Babysitting and Home Alone Courses | Barrie |
| St John Ambulance, Barrie Simcoe Muskoka, Car Seat Education | Barrie |
| St John Ambulance, Barrie Simcoe Muskoka, First Aid Training | Barrie |
| St John Ambulance, Barrie Simcoe Muskoka, Therapy Dog Program | Barrie |
| St John Ambulance Therapy Dogs, Therapy Dog Program | Barrie |
| St John's Anglican Church, Cookstown | Innisfil |
| St John's Presbyterian Church, Bradford | Bradford West Gwillimbury |
| St Paul the Apostle Catholic Church, Alliston | New Tecumseth |
| St Paul's Anglican Church, Barrie | Barrie |
| St Paul's United Church, Outreach and Community Support, Midland | Midland |
| STEM Camp, Barrie | Barrie |
| Stevenson Memorial Hospital, Mary McGill Community Mental Health Program | New Tecumseth |
| Stevenson Memorial Hospital, Obstetrics | New Tecumseth |
| Stevenson Memorial Hospital | New Tecumseth |
| Street Cats Rescue | Barrie |
| Stroke Recovery Association Barrie and District | Barrie |
| Super Feet | Innisfil |
| Superhero Kid's Hair with Care, Superhero Kids Hair With Care | Barrie |